November 1, 2017

AIM’s Pilot Program Request For Applications

By CC-Research

The Autophagy, Inflammation, and Metabolism (AIM) at the Center of Biomedical Research Excellence (CoBRE) is offering pilot awards in support of its mission to advance investigation into the role of autophagy in disease.

AIM’s Pilot Program provides grants to investigators with the intention that they will use the funds to generate data to apply for external funding (preferably through a variety of NIH mechanisms, but also through other funding sources). AIM is currently accepting grant applications for the 2018 funding period. Proposals must be received by 5:00PM MST on December 1, 2017.

For 2018, AIM pilot proposals should incorporate a basic science approach and should address the topic of autophagy in any disease context. Proposals that also incorporate investigation into inflammation or metabolism will be prioritized.

One of AIM’s goals is to increase the autophagy-based research community at UNM and within New Mexico. Use of AIM’s scientific core facilities is strongly encouraged for AIM-supported pilot projects.  AIM supports the following scientific core facilities and capabilities:

Autophagy core (Director: Larry Sklar, PhD)

  1. Animal resource: Breeding pairs of autophagy and autophagy-related gene transgenic mice for research in pilot, mPI and main personnel laboratories (IACUC approval needed)
  2. Cellomics high content microscopy: Quantitative microscopy for autophagy and lipid droplets as well as other intracellular profiles/organelles (e.g. lysosomes, peroxisomes, potentially mitochondira, nuclear translocation etc). Data generated are based on unbiased data collection and represent various numerical parameters (number/cell; area/cell, % overlap, etc.) + statistics on large number of cells.
  3. Amnis: as above (autophagy measures) for non-adherent cells.

Inflammation and Metabolism core (Director: Eric Prossnitz, PhD) 

  1. Seahorse: Oxidative phosphorylation vs glycolysis on adherent and non-adherent (special gel embedded) cells.
  2. Amnis: flow cytometry for intracellular cytokines, and other profiles in inflammatory/immune cells, etc.

Due Dates:  December 1, 2017 (Proposals Due)
Amount & Project Period:   up to $20,000  |  1-year
Links:  AIM CoBRE Pilot RFA

Tags: Funding, Funding Opps